Perpustakaan Digital

Advances in Multiple Sclerosis celebrates the 10th anniversary of Biomedicines. This Special Issue is a collection of remarkable papers addressing, among others, genetic markers, the multifactorial etiology of MS, the inflammatory contribution of the tertiary lymphoid structures, T-cell receptors, neurogenic bladder dynamics, and health disparities among minorities in the US. This collection constitutes an excellent source of information for interested MS researchers and professionals.

Land use change has had a fundamental impact on the livelihoods of people throughout the world. This Special Issue will focus on the research being conducted at the intersection of this land use change and the importance of maintaining landscapes that enrich humanity and our engagement with nature. In this Special Issue, we explore the value of landscapes that heighten the senses. Visual Resource Stewardship is an area of research that closely aligns with understanding how changes in the environment may be perceived and experienced. Understanding the tools, processes, and theories involved helps us to better understand how land use change impacts humanity, which is a critical endeavor in landscape planning. The goal of this Special Issue is to catalyze ideas and innovations between academia, practice, NGOs and government agencies working to address the analysis, planning, valuation, design and management of visual resources. Enclosed are articles that investigate, exemplify or theorize on the protection of visual resources in an era of major landscape changes on a regional, national and global scale and address multi-sensory topics at the intersection of people and the environment.

This essential collection, edited by Dr. Zeheng Wang and Dr. Jing-Kai Huang, unveils the latest advancements in semiconductor technology that are considered to be the cornerstone of the modern digital era. Spanning cutting-edge research in semiconductor materials, devices, and systems, this reprint is an indispensable guide through the innovative realms of microelectronics and nanotechnology.Dive into expert discussions on device architectures, from high-electron-mobility transistors to innovative designs resistant to extreme conditions. Explore the frontiers of material science and fabrication techniques, witnessing groundbreaking methods that enhance device performance and reliability. Uncover the evolving landscape of energy efficiency and power management, crucial for next-generation telecommunications and electric vehicles. Lastly, immerse yourself in the dynamic world of optoelectronics, where advancements in light-based technologies are redefining possibilities.Bringing togeth

The Special Issue, “Effect of the Modification of Catalysts on the Catalytic Performance”, should be of great interest to all researchers involved in this scientific area regarding the synthesis and characterization of various catalysts or catalytic materials; catalytic performance (activity and selectivity); synergetic effect; and the modification of catalysts or suitable promoters that are added to modify the catalyst structure. Related Books Effect of the Modification of Catalysts on the Catalytic Performance, 2nd Edition Chemistry & Materials Science Applied Catalysis in Chemical Industry: Synthesis, Catalyst Design, and Evaluation Chemistry & Materials Science New Concepts in Oxidation Processes Chemistry & Materials Science Catalytic Transformation of Renewables (Olefin, Bio-sourced, et. al) Chemistry & Materials Science Nanoparticle for Catalysis Biology & Life Sciences The recommendations have been generated using an AI system. About: About MDPI Books Advisory Board Lega

This reprint contains original research and review articles describing recent advances in our understanding of the transcriptional regulation of cardiac development and disease mechanisms. All articles were originally published in the International Journal of Molecular Sciences (IJMS). Related Books Transcriptional Regulation and Its Misregulation in Human Diseases Biology & Life Sciences Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation Biology & Life Sciences Translational Aspects of Cardiovascular Biology: From Bench to Bedside Biology & Life Sciences Cardiovascular Diseases: From Basic Research to Clinical Application Medicine & Pharmacology Advancements in Heart Failure Research Biology & Life Sciences ... The recommendations have been generated using an AI system. About: About MDPI Books Advisory Board Legal Information: MDPI Privacy Policy Terms and Conditions Terms of Use Accessibility Sales: Order and Delivery Indexing and Distribution Fur

This Special Issue opens a new field of research in certain emerging innovative instruments, because it provides an in-depth revision of the main aspects of institutions and instruments available for the management and governance of droughts and water scarcity. The key aspects that institutions may tackle not only include the increasing water scarcity in many regions around the world but also the increasing frequency and impact of droughts on economic and natural systems. Some of the included papers analyze critical issues, such as the state and future trends of water markets; the estimation of transaction costs when dealing with drought management; and the use of new instruments, such as insurance and water-rights entitlements, which include water security, water-pricing effects on the whole basin level, and intra- and inter-sectorial re-allocation. The important issues regarding non-conventional water supply and the governance of the new resources also feature as the focus of some

The Reprint Potential Health Benefits of Fruits and Vegetables III presents recent scientific findings on the role of fruits and vegetables in promoting human health and preventing disease. As plant-based foods, fruits and vegetables are widely recognized for their high content of bioactive compounds relevant to disease prevention and health maintenance. The contributions collected in this Reprint examine the composition of bioactive compounds in major fruit and vegetable species and explore their potential health effects when consumed fresh, processed, or evaluated through experimental models. In addition, the included studies investigate the biological mechanisms through which these compounds influence physiological processes and counteract the development of human pathologies. By bringing together multidisciplinary research, the Reprint provides an updated overview of current knowledge on the nutritional and functional value of fruits and vegetables and highlights their role in supporting preventive nutrition and health-related research.

Inflammation is a natural biological response to harmful stimuli like pathogens, injuries, or environmental stressors. However, when this response becomes chronic—often due to modern lifestyle factors like poor diet—it can lead to "lifestyle diseases". A wide range of chronic conditions, including cardiovascular diseases, cancer, diabetes, chronic kidney disease, non-alcoholic fatty liver disease, neurodegenerative, and autoimmune diseases, are now linked to inflammation. These conditions often involve oxidative stress, a harmful state caused by an imbalance between reactive oxygen and nitrogen species (ROS and RNS) and the body’s antioxidant defenses. Oxidative stress can further drive inflammation, creating a damaging cycle. The rising prevalence of chronic inflammatory disease has sparked interest in natural compounds with both antioxidant and anti-inflammatory effects. Marine organisms have emerged as a promising source of such bioactive compounds. From marine plants, algae, and fish to invertebrates like sea cucumbers, sponges, and soft corals and microorganisms such as fungi, microalgae, and archaea, these ocean lifeforms produce a wide array of therapeutic compounds. Given the growing scientific and therapeutic interest in marine bioactive compounds, we are pleased to launch the fourth edition of the Special Issue “Marine Anti-Inflammatory and Antioxidant Agents.”

Rice, a staple food for nearly half of the world's population, has long been a focus of agricultural and nutritional research. Rice (Oryza sativa), the first fully sequenced crop, holds the world’s largest single-species germplasm collection. This diversity is a valuable resource for improving rice varieties to enhance both human health and sustainability. The same potential exists for the lesser-known rice Oryza glaberrima. However, most people consume rice as milled white grains, which lack many of the nutritional benefits found in whole grain varieties such as brown, red, purple, and black rice. These whole grains are rich in fiber, vitamins, micronutrients, antioxidants, and bioactive phytochemicals, offering numerous health benefits. This Special Issue highlights the importance of whole grain rice, underutilized rice varieties, and by-products from rice processing, while exploring innovative approaches in rice cultivation, processing, and consumption that enhance its health benefits. The featured papers investigate how the full potential of rice can be unlocked, from climate-resilient agricultural techniques to value-added food processing, paving the way for a future where rice not only feeds the world but also improves global health.

Remote sensing is a powerful technique for characterizing and monitoring crop or vegetation properties at reasonable temporal and spatial resolutions. Remote sensing uses airborne and spaceborne platforms to collect various imageries and is widely applied for the vegetation monitoring of local- or large-scale interest concerning the effect of geophysical and climate parameters. The Special Issue highlights vegetation monitoring using remote sensing data acquired from satellite or unmanned aerial vehicle platforms. In addition to the optical data, thermal data is utilized to estimate crop yield or production, orchard water status, chlorophyll content, forest diversity mapping, or vegetation phenology. Related Books Crops and Vegetation Monitoring with Remote/Proximal Sensing II Environmental & Earth Sciences Remote Sensing of Vegetation Environmental & Earth Sciences Precision Agriculture and Crop Monitoring Based on Remote Sensing Methods Environmental & Earth Sciences UAS-Remote S

Almost all fields of dentistry are closely related to newly developed materials, and all clinical improvements often follow, or, in any case, go hand in hand with the creation and the development of innovative and higher performing materials, instruments, and equipment. Thanks to contemporary applications of dental materials, the effectiveness of clinical dentistry has made remarkable advances. In recent years, thanks to digital technology and the frenetic development of the dental industry, new materials have been developed and proposed in many fields of dentistry: prosthesis, restorative dentistry, endodontics, implantology, and orthodontics. Unfortunately, as often happens, this productive challenge is not always accompanied by valid scientific research, and consequently the clinician finds new materials at their disposal that are not necessarily better than the old. Further studies are needed to gain relevant evidence for all recently introduced dental materials. This reprint i

Phospholipases are a ubiquitous group of enzymes that hydrolyze ester bonds within membrane phospholipids. These enzymes serve multiple biological functions that go far beyond a mere membrane remodeling role in cellular homeostasis; they also play key functions in nutrient digestion and the regulated formation of bioactive lipids involved in cell signaling. It is to the latter function, critical to life, that this book is primarily concerned with. All the chapters are written by renowned experts in the area, and provide forefront information on the role phospholipases in a number of physiological and pathophysiological settings. Related Books Sphingolipids Biology & Life Sciences Emerging Role of Lipids in Metabolism and Disease Biology & Life Sciences ... Bioactive Lipids and Lipidomics 2018 Biology & Life Sciences Membrane Proteins: Structure, Function and Motion Biology & Life Sciences ... Advances in Lipidomics: Biomedicine, Nutrients and Methodology Public Health & Healthcare .

Bioactive compounds and drugs are designed and screened on the basis of specific molecular targets as well as via the identification of active ingredients from traditional medicine or by serendipitous discovery. The development of novel therapeutic strategies not only requires a deep knowledge of the molecular processes and the cellular pathways involved in each pathological condition and disease, but also the specific protein targets and the effects of drug binding on protein conformation and activity. Understanding of how drugs can modify and modulate specific cellular pathways and functions will be helpful during the process of drug development and clinical trials. Related Books Recent Developments on Protein–Ligand Interactions Biology & Life Sciences Comprehending Molecular Targets Biology & Life Sciences ... Natural Bioactives as Leading Molecules for Drug Development Biology & Life Sciences Discovery of Bioactive Compounds from Natural Organisms and Their Molecular Mechanisms

The global energy landscape is undergoing a profound transformation as conventional oilfields face declining productivity and unconventional reservoirs—such as tight oil, shale gas, and heavy oil—demand advanced recovery technologies. This Special Issue, “New Advances in Oil, Gas and Geothermal Reservoirs—3rd Edition,” presents cutting-edge research addressing three critical areas: the optimization of mature and unconventional reservoir development, the integration of big data and artificial intelligence (AI) in oil and gas field management, and innovations in natural gas storage, transportation, and sequestration. The collected studies employ state-of-the-art numerical modeling, experimental methods, and data-driven approaches to tackle challenges such as improving waterflood efficiency in complex reservoirs, enhancing heavy-oil thermal recovery, and ensuring safe underground gas storage. By combining detailed geological characterization with AI-assisted decision-making, this issue provides a comprehensive foundation for the sustainable and efficient exploitation of geo-energy resources, supporting the global transition toward cleaner and more resilient energy systems.

The legume family is economically important and is one of the most important sources of starch, protein, oil, and vegetables for human food around the world, playing an irreplaceable role in guaranteeing human food security. The pulses are an important component of the response of the Food and Agriculture Organization of the United Nations (FAO) in emergencies. However, the frequent occurrence of diseases, pests, and weeds restrict the high and stable yield of legume crops. Major diseases of legumes include root rots, bacterial blights, and mosaic diseases. In addition, damage caused by malignant weeds, nematodes, and sap-sucking/-chewing insects is also included as a constraint on legume production. This Special Issue is focused on 13 selected topics (12 articles and 1 editorial) from different universities and research institutes. The research fields covered include mechanisms of resistance to pests and diseases, identification and monitoring of diseases, alternative control strategies, weed management, and drone-mounted multispectral imaging technology. Current problems in the prevention and control of legume crop diseases, pests, and weeds are discussed with a view to providing subsequent research and applications of key pest- and disease-monitoring and control technologies with reference points.

Ageing induces an increased prevalence of chronic skeletal diseases such as osteoporosis, osteoarthritis, and intervertebral disc degeneration/herniation. Dietary nutrition is an essential factor for skeletal health, the level of which is relatively easy to modify. For certain kinds of nutrients, including calcium and vitamin D, adequate dietary intake helps to reduce the risk of bone diseases. That said, some other kinds of dietary constituents, like fat and carbohydrates, play a much more complex role in bone health. It is both challenging and promising to study the role of dietary factors in degenerative bone and joint disorders, and to achieve “healthy ageing” with the adjustment of dietary nutrition. This Special Issue, entitled “Dietary Factors in Bone Health”, highlights the importance of dietary factors for bone health, including both basic and clinical studies. The papers collected in this Special Issue focus on the effects of calcium, vitamin D, vitamin K, and polyphenols, as well as other nutritional factors, on bone health around the world, providing the latest understanding in the development of the field.

Nature has represented and still represents a great pool of biologically active compounds and, at the same time, is a source of inspiration. In the first phase, the researchers turned their attention to the new compounds isolated from plants and their characterization in terms of their beneficial effects on human health. Recently, however, there have been extensive studies on the synthesis of compounds analogous to plant-derived compounds in order to prevent or treat diseases such as diabetes, obesity, chronic liver diseases, respiratory diseases, cardiovascular diseases, cancer, and so on. One of the mechanisms involved in the beneficial effect on human health is represented by plant-derived compounds’ anti-inflammatory effects. Related Books Anti-oxidant and Anti-inflammatory Properties of Natural Compounds Biology & Life Sciences ... Targeting Inflammation and Inflammatory-Related Diseases with Natural Bioactives Medicine & Pharmacology Role of Natural Compounds in Inflammation a

Robotics and intelligent systems are key technologies to promote efficient and innovative applications in the most diverse domains (industry, healthcare, agriculture, construction, mobility, etc.), performing and supporting activities that are not suitable to be performed by humans. Such activities are frequently time-consuming, repetitive tasks with low added value, which are physically demanding and/or dangerous. Nevertheless, robotics and intelligent systems face several scientific and technological challenges related to their integration and interoperability with other systems, safety, flexibility, re-configurability and autonomy. These challenges are especially relevant when robots operate in real unstructured environments and share a workspace with humans and other equipment. This reprint collects research achievements, ideas, and applications regarding advanced intelligent robotic systems, covering diverse technologies and application domains. Generically, the contributions co

This Special Issue, “Plant Oxidative Stress: Biology, Physiology, and Mitigation”, published 11 original research works and 1 review article that discussed the various aspects of ROS Biology, metabolism, and the physiological mechanisms and approaches to mitigating oxidative stress. These types of research studies show further directions for the development of crop plants that are tolerant to abiotic stress in the era of climate change. Related Books Oxidative Stress in Plants Biology & Life Sciences ... Approaches in Enhancing Antioxidant Defense in Plants Biology & Life Sciences Oxidative Stress and Antioxidant Defense in Crop Plants, 2nd Edition Biology & Life Sciences ... Oxidative Stress and Antioxidant Defense in Crop Plants Biology & Life Sciences ... Mitigation Strategies and Tolerance of Plants to Abiotic Stresses Environmental & Earth Sciences The recommendations have been generated using an AI system. About: About MDPI Books Advisory Board Legal Information: MDPI Pri

This book entitled “Chemical Symmetry Breaking” is a collective volume of state-of-the-art reports on unique nonlinear chemical and physical symmetry-breaking phenomena that were experimentally observed upon a thermally or photochemically induced phase transition in various organic condensed phases, such as metastable liquid crystals, crystals, amorphous solids, and colloidal polymer materials, only under nonequilibrium conditions. Each author summarizes the introductory section in simple terms but in detail for beginners in this field. We wish that many readers familiarize themselves with the general concepts and features of nonlinear and nonequilibrium (or out of equilibrium) complexity theory, which govern a variety of unique dynamic behaviors observed in chemistry, physics, life science and other fields, so that they may discover novel symmetry-breaking phenomena in their own research areas. Related Books Symmetry Breaking in Cells and Tissues Biology & Life Sciences ... Broken Sy

This Special Issue explores how network pharmacology is reshaping the discovery and development of medicines derived from natural products in the context of modern systems biology. Moving beyond reductionist single‑target paradigms, the collected articles demonstrate how multi‑component botanicals, traditional herbal medicines, and purified natural compounds exert therapeutic effects through interconnected molecular networks and pathway interactions. The contributions to this Issue integrate computational network analysis, artificial intelligence, molecular docking, and multi‑omics technologies with experimental validation, highlighting new strategies to address complex, multifactorial diseases. The Issue covers a broad spectrum of therapeutic areas, including inflammatory and infectious diseases, metabolic and neurodegenerative disorders, cancer drug resistance, and stress‑ and aging‑related conditions. Particular attention is given to multitarget mechanisms, immunomodulation, metabolic regulation, and the concept of adaptogens as resilience‑supporting agents. Together, these studies illustrate methodological advances, translational opportunities, and regulatory challenges in contemporary natural product research. By bridging traditional medical knowledge with cutting‑edge pharmacological tools, this Special Issue provides a forward‑looking framework for the rational development of safe, effective, and holistic therapies based on natural products.

With the complete prohibition of feed antibiotic additives in many countries and regions, including China, the United States, and Europe, studying and developing efficient new green feed additives with plant extracts and their ability to mitigate various problems in livestock and poultry breeding have gradually become a key focus of animal science research. In this Special Issue, we compiled research articles and reviews on the effects of plant extracts on meat quality, intestinal flora, resistance to disease, and stress in edible animals, highlighting current knowledge and future directions in this field.

This Special Issue is entitled “Gurus, Priestesses, Saints, Mediums, and Yoginis: Holy Women as ‘Influencers’ in Hindu Culture” and features emerging research on holy women from different disciplinary perspectives. Applying the “influencer” concept to the study of religion, the volume explores the varieties of strategies that holy women use for gaining and expressing power in diverse roles. It examines different concepts of holiness and leadership for men and women, the role of charisma, and the arenas of activity and accomplishment for holy women in India and abroad. By relating a new idea—that of the ‘influencer’—to the study of women and religious authority, the Issue contributes fresh and refined analyses and explanatory models toward a greater understanding of women’s evolving relationship to the Hindu tradition. As the co-editors, we are grateful to our team of contributors, peer reviewers, and the Religions editorial staff for their collaboration and enthusiasm in bringing this volume to completion.

This Special Issue is a continuation of our previous Special Issue “Molecular Mechanisms of Synaptic Plasticity: Dynamic Changes in Neurons Functions”. With the aim to present good research papers provided by specialists, this Special Issue published basic research and pre-clinical research articles, case reports, case series or clinical image articles, short communications, and review articles. Related Books Molecular Mechanisms of Synaptic Plasticity: Dynamic Changes in Neurons Functions Biology & Life Sciences Brain Stimulation and Neuroplasticity- Series II Biology & Life Sciences New Insights into Molecular Mechanisms Underlying Neurodegenerative Disorders Medicine & Pharmacology Genetic, Epigenetic, Environmental, and Pharmacological Models for Neuroscience, Neurologic Diseases, and Psychiatric Disorders: Advancement in Bench-to-Bedside Translational Research Biology & Life Sciences ... Neurodegeneration in Cognitive Impairment and Mood Disorders for Experimental, Clinical and